ZFIN is now using GRCz12tu for Genomic Data
Gene
prdm12b
- ID
- ZDB-GENE-041114-172
- Name
- PR domain containing 12b
- Symbol
- prdm12b Nomenclature History
- Previous Names
-
- zgc:101606
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable histone methyltransferase binding activity. Acts upstream of or within hemopoiesis; negative regulation of transcription by RNA polymerase II; and ventral spinal cord interneuron specification. Predicted to be active in nucleus. Is expressed in several structures, including basal plate midbrain region; central nervous system; cranial ganglion; ectoderm; and midbrain neural keel. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 8. Orthologous to human PRDM12 (PR/SET domain 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101606 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary sensory and autonomic neuropathy type 8 | Alliance | Neuropathy, hereditary sensory and autonomic, type VIII | 616488 |
Domain, Family, and Site Summary
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prdm12b-201
(1)
|
Ensembl | 3,027 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers