Gene
trmt10c
- ID
- ZDB-GENE-041114-12
- Name
- tRNA methyltransferase 10C, mitochondrial RNase P subunit
- Symbol
- trmt10c Nomenclature History
- Previous Names
-
- rg9mtd1
- wu:fb53e06
- zgc:103570 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 30. Orthologous to human TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103570 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 30 | Alliance | Combined oxidative phosphorylation deficiency 30 | 616974 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR016009 | tRNA methyltransferase TRMD/TRM10-type domain |
| Domain | IPR025812 | tRNA methyltransferase 10 homolog C, TRM10-type domain |
| Domain | IPR028564 | tRNA methyltransferase TRM10-type domain |
| Homologous_superfamily | IPR038459 | tRNA methyltransferase TRM10-type domain superfamily |
Domain Details Per Protein
| Protein | Length | tRNA methyltransferase 10 homolog C, TRM10-type domain | tRNA methyltransferase TRM10-type domain | tRNA methyltransferase TRM10-type domain superfamily | tRNA methyltransferase TRMD/TRM10-type domain |
|---|---|---|---|---|---|
|
UniProtKB:B8JM40
|
403 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trmt10c-202
(1)
|
Ensembl | 1,683 nt | ||
| mRNA |
trmt10c-203
(1)
|
Ensembl | 1,139 nt | ||
| ncRNA |
trmt10c-003
(1)
|
Ensembl | 538 nt |
Interactions and Pathways
No data available
Plasmids
No data available