Gene

fgf13a

ID

ZDB-GENE-041114-101

Name

fibroblast growth factor 13a

Symbol

fgf13a Nomenclature History

Previous Names

fgf13
zgc:101784

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable sodium channel regulator activity. Predicted to be involved in neurogenesis. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including filopodium; growth cone; and sarcolemma. Predicted to be active in cytoplasm and nucleus. Is expressed in basal plate midbrain region; heart; myotome; nervous system; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 90 and non-syndromic X-linked intellectual disability. Orthologous to human FGF13 (fibroblast growth factor 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101784 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fgf13a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 90	Alliance	Developmental and epileptic encephalopathy 90	301058
		Intellectual developmental disorder, X-linked 110	301095

Associated With fgf13a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR002209	Fibroblast growth factor family
Homologous_superfamily	IPR008996	Cytokine IL1/FGF

Domain Details Per Protein

Protein	Length	Cytokine IL1/FGF	Fibroblast growth factor family
UniProtKB:A0A8M9PZ61 InterPro	199
UniProtKB:Q5TKR2 InterPro	246
UniProtKB:Q5U3Q2 InterPro	193
UniProtKB:E7F5G0 InterPro	255

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fgf13a-201 (1) Ensembl	Ensembl	1,371 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-202 (1) Ensembl	Ensembl	1,130 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-203 (1) Ensembl	Ensembl	2,383 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-204 (1) Ensembl	Ensembl	646 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-205 (1) Ensembl	Ensembl	659 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-206 (1) Ensembl	Ensembl	777 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-207 (1) Ensembl	Ensembl	1,144 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-208 (1) Ensembl	Ensembl	1,203 nt	Select Tool ZFIN BLAST
mRNA	fgf13a-209 (1) Ensembl	Ensembl	1,445 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations