Gene
mybl1
- ID
- ZDB-GENE-041111-281
- Name
- v-myb avian myeloblastosis viral oncogene homolog-like 1
- Symbol
- mybl1 Nomenclature History
- Previous Names
-
- im:7151384
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in mitotic cell cycle and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in blood and telencephalon. Orthologous to human MYBL1 (MYB proto-oncogene like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151384 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa45831 | Allele with one point mutation | Unknown | Splice Site | ENU |
1 - 1 of 1
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | C-myb, C-terminal | Homedomain-like superfamily | Myb domain | SANT/Myb domain | Transcription factors Myb-like | Transcription regulator Wos2-domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FFJ6 | InterPro | 740 | ||||||
| UniProtKB:A0A8M6YWG1 | InterPro | 739 | ||||||
| UniProtKB:A0A8M6YYA7 | InterPro | 742 | ||||||
| UniProtKB:A0A8M6YVU1 | InterPro | 710 | ||||||
| UniProtKB:A0A8M2B9R3 | InterPro | 743 | ||||||
| UniProtKB:E9QEE0 | InterPro | 707 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-162H1 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7151384 | Thisse et al., 2004 |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_005162751 (1) | 4424 nt | ||
| Genomic | GenBank:BX470095 (1) | 209513 nt | ||
| Polypeptide | UniProtKB:A0A8M2B9R3 (1) | 743 aa |
- Zhang, J., Li, P., Sun, L., Jiang, N., Guo, W., Wang, J., Gao, F., Li, J., Li, H., Zhang, J., Mu, H., Hu, Y., Cui, X. (2023) Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37:e22927e22927
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Sundström, G., Dreborg, S., and Larhammar, D. (2010) Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates. PLoS One. 5(5):e10512
1 - 4 of 4
Show