Gene

e2f8

ID
ZDB-GENE-041111-260
Name
E2F transcription factor 8
Symbol
e2f8 Nomenclature History
Previous Names
  • im:7149356 (1)
  • si:ch211-215h6.2 (1)
  • wu:fc06b06
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in motor neuron axon guidance; regulation of transcription, DNA-templated; and vasculature development. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in several structures, including axis; caudal vein plexus; eye; liver; and proliferative region. Orthologous to human E2F8 (E2F transcription factor 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Weijts et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With e2f8 Human Ortholog
No data available
Associated With e2f8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003316 E2F/DP family, winged-helix DNA-binding domain
Family IPR015633 E2F Family
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length E2F/DP family, winged-helix DNA-binding domain E2F Family Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:F1QC93 237
UniProtKB:E9QE44 218
UniProtKB:Q58EH2 583
UniProtKB:F1QZ88 917
UniProtKB:F1R6D8 236
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations