Gene

angptl4

ID
ZDB-GENE-041111-222
Name
angiopoietin-like 4
Symbol
angptl4 Nomenclature History
Previous Names
  • fiaf (1)
  • im:7144703
  • si:rp71-39b20.7 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have enzyme inhibitor activity and signaling receptor binding activity. Involved in apoptotic process involved in blood vessel morphogenesis and response to bacterium. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in endocrine pancreas; intestinal epithelium; intestine; and liver. Orthologous to human ANGPTL4 (angiopoietin like 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Serbanovic-Canic et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With angptl4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Plasma triglyceride level QTL, low 615881
Associated With angptl4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020837 Fibrinogen, conserved site
Domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Family IPR050373 Fibrinogen C-terminal domain-containing protein
Homologous_superfamily IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Homologous_superfamily IPR036056 Fibrinogen-like, C-terminal
Domain Details Per Protein
Protein Length Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 Fibrinogen, conserved site Fibrinogen C-terminal domain-containing protein Fibrinogen-like, C-terminal
UniProtKB:A0A8M1NYZ0 460
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations