Gene
taar10
- ID
- ZDB-GENE-041014-49
- Name
- trace amine-associated receptor 10
- Symbol
- taar10 Nomenclature History
- Previous Names
-
- si:dkey-7c18.8 (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and serotonin binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; adenylate cyclase-inhibiting serotonin receptor signaling pathway; and chemical synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in dendrite and plasma membrane. Is expressed in olfactory epithelium. Orthologous to human TAAR1 (trace amine associated receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Hussain et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa43524 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Trace Amine-Associated Receptor | Trace amine associated receptor family |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PH38 | InterPro | 353 | ||||
| UniProtKB:A3KP34 | InterPro | 342 | ||||
| UniProtKB:A0A8M3ALS3 | InterPro | 354 | ||||
| UniProtKB:A0AB13AAW0 | InterPro | 342 | ||||
| UniProtKB:A0AB32T8V1 | InterPro | 353 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
taar10-201
(1)
|
Ensembl | 1,367 nt | ||
| ncRNA |
taar10-002
(1)
|
Ensembl | 499 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-7C18 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-246E3 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:162912 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001083038 (1) | 1385 nt | ||
| Genomic | GenBank:AL929507 (1) | 214404 nt | ||
| Polypeptide | UniProtKB:A0A8M3ALS3 (1) | 354 aa |
No data available
- Saraiva, L.R., Ahuja, G., Ivandic, I., Syed, A.S., Marioni, J.C., Korsching, S.I., Logan, D.W. (2015) Molecular and neuronal homology between the olfactory systems of zebrafish and mouse. Scientific Reports. 5:11487
- Hussain, A., Saraiva, L.R., Ferrero, D.M., Ahuja, G., Krishna, V.S., Liberles, S.D., and Korsching, S.I. (2013) High-affinity olfactory receptor for the death-associated odor cadaverine. Proceedings of the National Academy of Sciences of the United States of America. 110(48):19579-19584
- Hussain, A., Saraiva, L.R., and Korsching, S.I. (2009) Positive Darwinian selection and the birth of an olfactory receptor clade in teleosts. Proceedings of the National Academy of Sciences of the United States of America. 106(11):4313-4318
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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