ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
zyg11
- ID
- ZDB-GENE-041014-17
- Name
- zyg-11 family member, cell cycle regulator
- Symbol
- zyg11 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - si:ch211-11m18.3
- zgc:136612 (1)
- zgc:152675
 
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within cranial skeletal system development and notochord development. Predicted to be part of Cul2-RING ubiquitin ligase complex. Is expressed in female organism. Orthologous to several human genes including ZYG11B (zyg-11 family member B, cell cycle regulator).
- Genome Resources
- Note
- None
- Comparative Information
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- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
- 1 Figure from Tingaud-Sequeira et al., 2020
- Cross-Species Comparison
- Alliance
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Type | InterPro ID | Name | 
|---|---|---|
| Domain | IPR055142 | Protein zer-1 homolog-like, C-terminal domain | 
| Family | IPR051341 | Zyg-11-related ubiquitin ligase adapter protein | 
| Homologous_superfamily | IPR011989 | Armadillo-like helical | 
| Homologous_superfamily | IPR016024 | Armadillo-type fold | 
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily | 
| Repeat | IPR000225 | Armadillo | 
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | Armadillo | Armadillo-like helical | Armadillo-type fold | Leucine-rich repeat domain superfamily | Protein zer-1 homolog-like, C-terminal domain | Zyg-11-related ubiquitin ligase adapter protein | 
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5TYQ1 | InterPro | 746 | 
- Genome Browsers
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
