Gene
nln
- ID
- ZDB-GENE-041010-216
- Name
- neurolysin (metallopeptidase M3 family)
- Symbol
- nln Nomenclature History
- Previous Names
-
- thop1
- zgc:92589
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide metabolic process and proteolysis. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial intermembrane space. Is expressed in hypaxial myotome region; musculature system; myotome; and pectoral fin musculature. Orthologous to human NLN (neurolysin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92589 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001567 | Peptidase M3A/M3B catalytic domain |
| Family | IPR045090 | Peptidase M3A/M3B |
| Homologous_superfamily | IPR024077 | Neurolysin/Thimet oligopeptidase, domain 2 |
| Homologous_superfamily | IPR024079 | Metallopeptidase, catalytic domain superfamily |
| Homologous_superfamily | IPR024080 | Neurolysin/Thimet oligopeptidase, N-terminal |
Domain Details Per Protein
| Protein | Additional Resources | Length | Metallopeptidase, catalytic domain superfamily | Neurolysin/Thimet oligopeptidase, domain 2 | Neurolysin/Thimet oligopeptidase, N-terminal | Peptidase M3A/M3B | Peptidase M3A/M3B catalytic domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q5XIZ1 | InterPro | 660 | |||||
| UniProtKB:A0A8M6Z2X4 | InterPro | 589 | |||||
| UniProtKB:A0A2R8RVE2 | InterPro | 710 | |||||
| UniProtKB:A0A8M2B1N0 | InterPro | 687 | |||||
| UniProtKB:A0AB32U2C7 | InterPro | 690 |
Interactions and Pathways
No data available
Plasmids
No data available