ZFIN is now using GRCz12tu for Genomic Data
Gene
osbpl7
- ID
- ZDB-GENE-041010-212
- Name
- oxysterol binding protein-like 7
- Symbol
- osbpl7 Nomenclature History
- Previous Names
-
- osbpl6
- wu:fu06e07
- zgc:92595
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cholesterol binding activity. Predicted to act upstream of or within lipid transport. Predicted to be located in cytoplasm. Predicted to be active in several cellular components, including cytosol; nuclear membrane; and perinuclear endoplasmic reticulum. Is expressed in EVL; epidermis; periderm; pharynx; and retina. Orthologous to human OSBPL7 (oxysterol binding protein like 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139902 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Duara et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018494 | Oxysterol-binding protein, conserved site |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR041680 | Pleckstrin homology domain 8 |
| Family | IPR000648 | Oxysterol-binding protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR037239 | Oxysterol-binding protein superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Oxysterol-binding protein | Oxysterol-binding protein, conserved site | Oxysterol-binding protein superfamily | PH-like domain superfamily | Pleckstrin homology domain | Pleckstrin homology domain 8 |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AY80 | InterPro | 896 | ||||||
| UniProtKB:A0A8M9QE65 | InterPro | 902 | ||||||
| UniProtKB:A0A8M3B7C6 | InterPro | 879 | ||||||
| UniProtKB:A0A8M3BE40 | InterPro | 910 | ||||||
| UniProtKB:Q5XIY7 | InterPro | 888 | ||||||
| UniProtKB:A0A8M3B4J5 | InterPro | 857 | ||||||
| UniProtKB:A0AB32TXW4 | InterPro | 888 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
osbpl7-201
(1)
|
Ensembl | 3,822 nt | ||
| mRNA |
osbpl7-202
(1)
|
Ensembl | 867 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers