Gene

osbpl7

ID

ZDB-GENE-041010-212

Name

oxysterol binding protein-like 7

Symbol

osbpl7 Nomenclature History

Previous Names

osbpl6
wu:fu06e07
zgc:92595

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have cholesterol binding activity and sterol transporter activity. Predicted to be involved in lipid transport. Predicted to localize to cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Is expressed in EVL; epidermis; periderm; pharynx; and retina. Orthologous to human OSBPL7 (oxysterol binding protein like 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7139902 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With osbpl7 Human Ortholog

No data available

Associated With osbpl7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018494	Oxysterol-binding protein, conserved site
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR041680	Pleckstrin homology domain 8
Family	IPR000648	Oxysterol-binding protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR037239	Oxysterol-binding protein superfamily

Domain Details Per Protein

Protein	Length	Oxysterol-binding protein	Oxysterol-binding protein, conserved site	Oxysterol-binding protein superfamily	PH-like domain superfamily	Pleckstrin homology domain	Pleckstrin homology domain 8
UniProtKB:A0A8M3AY80 InterPro	896
UniProtKB:A0A8M9QE65 InterPro	902
UniProtKB:A0A8M3B7C6 InterPro	879
UniProtKB:A0A8M3BE40 InterPro	910
UniProtKB:Q5XIY7 InterPro	888
UniProtKB:A0A8M3B4J5 InterPro	857

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	osbpl7-201 (1) Ensembl	Ensembl		3,822 nt	Select Tool ZFIN BLAST
mRNA	osbpl7-202 (1) Ensembl	Ensembl		867 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl
Note: Woods, et al. (2005. Genome Res. 15:1307-1914.) reported orthology to OSBPL6 supported by amino acid sequence identity and conserved location.

Citations