Gene

cldn5b

ID
ZDB-GENE-041010-140
Name
claudin 5b
Symbol
cldn5b Nomenclature History
Previous Names
  • zgc:103419
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to localize to bicellular tight junction and plasma membrane. Is expressed in several structures, including cardiovascular system; eye; integument; pleuroperitoneal region; and ventral mesoderm. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Bonkhofer et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cldn5b Human Ortholog
No data available
Associated With cldn5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017974 Claudin, conserved site
Family IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Family IPR006187 Claudin
Domain Details Per Protein
Protein Length Claudin Claudin, conserved site PMP-22/EMP/MP20/Claudin superfamily
UniProtKB:F1R5J2 220
UniProtKB:Q5XJD5 217
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations