Gene
csrp3
- ID
- ZDB-GENE-041010-119
- Name
- cysteine and glycine-rich protein 3 (cardiac LIM protein)
- Symbol
- csrp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable actinin binding activity. Predicted to be a structural constituent of muscle. Acts upstream of or within heart contraction; response to muscle stretch; and sarcomere organization. Predicted to be active in Z disc and nucleus. Is expressed in musculature system; pericardial region; and trunk. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Orthologous to human CSRP3 (cysteine and glycine rich protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 1M | Alliance | ?Cardiomyopathy, dilated, 1M | 607482 |
| hypertrophic cardiomyopathy 12 | Alliance | Cardiomyopathy, hypertrophic, 12 | 612124 |
1 - 2 of 2
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001781 | Zinc finger, LIM-type |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger, LIM-type |
|---|---|---|---|
| UniProtKB:A0A8M1P2D0 | InterPro | 222 | |
| UniProtKB:F1QJC0 | InterPro | 193 |
1 - 2 of 2
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available