Gene

atl3

ID
ZDB-GENE-041010-109
Name
atlastin 3
Symbol
atl3 Nomenclature History
Previous Names
  • im:6911985
  • zgc:103512
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in endoplasmic reticulum organization and protein homooligomerization. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hereditary sensory neuropathy type 1F. Orthologous to human ATL3 (atlastin GTPase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atl3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary sensory neuropathy type 1F Alliance Neuropathy, hereditary sensory, type IF 615632
Associated With atl3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003191 Guanylate-binding protein/Atlastin, C-terminal
Domain IPR015894 Guanylate-binding protein, N-terminal
Domain IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036543 Guanylate-binding protein, C-terminal domain superfamily
Domain Details Per Protein
Protein Length GB1/RHD3-type guanine nucleotide-binding (G) domain Guanylate-binding protein/Atlastin, C-terminal Guanylate-binding protein, C-terminal domain superfamily Guanylate-binding protein, N-terminal P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q5XJ96 513
UniProtKB:A2CEM3 113
UniProtKB:A2CEM4 513
UniProtKB:A0A2R8RX84 518
UniProtKB:F6PA68 165
UniProtKB:A2CEM2 279
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations