Gene
ppl
- ID
- ZDB-GENE-041008-196
- Name
- periplakin
- Symbol
- ppl Nomenclature History
- Previous Names
-
- cb180 (1)
- im:7140067
- im:7149519
- sb:cb180
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Predicted to be involved in intermediate filament cytoskeleton organization and wound healing. Predicted to be located in cornified envelope; cytoskeleton; and desmosome. Predicted to be active in cytoplasm and membrane. Predicted to colocalize with intermediate filament. Is expressed in several structures, including EVL; digestive system; fin; periderm; and sensory system. Orthologous to human PPL (periplakin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb180 (7 images)
- IMAGE:7140067 (6 images)
- IMAGE:7149519 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Inaba et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Desmoplakin, SH3 domain | Periplakin/Envoplakin, N-terminal | Plakin | Plakin repeat superfamily | Plectin repeat | SH3 domain | Spectrin/alpha-actinin |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAS2 | InterPro | 1754 | |||||||
| UniProtKB:A0A286YAI4 | InterPro | 1752 |
Interactions and Pathways
No data available
Plasmids
No data available