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Gene

myt1la

ID
ZDB-GENE-041001-172
Name
myelin transcription factor 1-like, a
Symbol
myt1la Nomenclature History
Previous Names
  • si:dkey-260n20.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human MYT1L (myelin transcription factor 1 like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Blanchet et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myt1la Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant non-syndromic intellectual disability 39 Alliance Mental retardation, autosomal dominant 39 616521
Associated With myt1la Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013681 Myelin transcription factor 1
Homologous_superfamily IPR036060 Zinc finger, C2H2C-type superfamily
Repeat IPR002515 Zinc finger, C2H2C-type
Domain Details Per Protein
Protein Length Myelin transcription factor 1 Zinc finger, C2H2C-type Zinc finger, C2H2C-type superfamily
UniProtKB:Q08C79 549
UniProtKB:Q5TZG3 1257
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations