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ZIRC
ZFIN ID: ZDB-GENE-041001-135
Gene Name: mitogen-activated protein kinase kinase kinase 7
Gene Symbol: map3k7
Sequence Ontology ID : SO:0000704

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Previous Names: si:ch211-225h9.1 (1), tak1 (1), zgc:110612 (1)

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have MAP kinase kinase kinase activity. Involved in blood vessel morphogenesis. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human MAP3K7  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110612]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021478Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa230 Point Mutation Unknown Premature Stop ENU
    sa23699 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH map3k7 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Frontometaphyseal dysplasia 2 617137
    Cardiospondylocarpofacial syndrome 157800
    DISEASE ASSOCIATED WITH map3k7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel morphogenesis (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA map3k7-004 (1) 909
    map3k7-006 (1) 915
    mRNA map3k7-201 (1) 4042
    map3k7-202 (1) 870
    map3k7-203 (1) 820
    aberrant processed transcript map3k7-205 (1) 871
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM map3k7 No data available
    MARKER RELATIONSHIPS
    map3k7Contained in: [BAC] CH211-225H9 (1) (order this)
    map3k7Encodes: [cDNA] MGC:110612 (1) (order this), MGC:191408 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001020750 (1) 2040bp
    Genomic GenBank:BX119992 (1) 174275bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IVJ5 (1) 578aa
    Sequence Clusters UniGene:80386 (1)
    Sequence Information (all 28)
    ORTHOLOGY for map3k7 (Chr: 20)
    CITATIONS (30)