Gene

cnot3a

ID
ZDB-GENE-040927-6
Name
CCR4-NOT transcription complex, subunit 3a
Symbol
cnot3a Nomenclature History
Previous Names
  • fb73b06
  • fc17h07
  • wu:fb73b06
  • wu:fc17h07
  • zgc:92813
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Acts upstream of or within digestive tract development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Is expressed in several structures, including gut; head; heart; integument; and testis. Orthologous to human CNOT3 (CCR4-NOT transcription complex subunit 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Delacruz et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Delacruz et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnot3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with speech delay, autism, and dysmorphic facies 618672
1 - 1 of 1
Associated With cnot3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007207 CCR4-Not complex component, Not N-terminal domain
Domain IPR007282 NOT2/NOT3/NOT5, C-terminal
Family IPR012270 CCR4-NOT complex, subunit 3/ 5
Family IPR040168 Not2/Not3/Not5
Homologous_superfamily IPR038635 CCR4-NOT complex subunit 2/3/5, C-terminal domain superfamily
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length CCR4-Not complex component, Not N-terminal domain CCR4-NOT complex subunit 2/3/5, C-terminal domain superfamily CCR4-NOT complex, subunit 3/ 5 Not2/Not3/Not5 NOT2/NOT3/NOT5, C-terminal
UniProtKB:E9QGK5 InterPro 901
UniProtKB:F1Q4L8 InterPro 908
UniProtKB:A0A8M9P7W2 InterPro 906
1 - 3 of 3
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cnot3a-201 (1) Ensembl 4,220 nt
mRNA cnot3a-203 (1) Ensembl 4,198 nt
ncRNA cnot3a-003 (1) Ensembl 634 nt
1 - 3 of 3
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations