opcml

ID

ZDB-GENE-040927-3

Name

opioid binding protein/cell adhesion molecule-like

Symbol

opcml Nomenclature History

Previous Names

zgc:92901

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be involved in heterophilic cell-cell adhesion and regulation of synapse assembly. Predicted to be located in side of membrane. Predicted to be active in plasma membrane. Is expressed in nervous system and otic vesicle. Human ortholog(s) of this gene implicated in hypertension; ovarian cancer; and primary open angle glaucoma. Orthologous to several human genes including OPCML (opioid binding protein/cell adhesion molecule like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0634 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With opcml Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
ovarian cancer	Alliance	Ovarian cancer, somatic	167000

Associated With opcml Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR050876	IgLON domain-containing protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily