Gene

rgra

ID

ZDB-GENE-040924-6

Name

retinal G protein coupled receptor a

Symbol

rgra Nomenclature History

Previous Names

rgr1 (1)
rgr
zgc:110660

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have G protein-coupled photoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; cellular response to light stimulus; and phototransduction. Predicted to localize to integral component of plasma membrane and photoreceptor outer segment. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 44. Is expressed in several structures, including gut; heart; nervous system; testis; and yolk syncytial layer. Orthologous to human RGR (retinal G protein coupled receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7165454 (19 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rgra Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 44	Alliance	Retinitis pigmentosa 44	613769

Associated With rgra Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR001793	Retinal pigment epithelium GPCR
Family	IPR050125	G-protein coupled receptor opsins