Gene

gpx1b

ID
ZDB-GENE-040912-60
Name
glutathione peroxidase 1b
Symbol
gpx1b Nomenclature History
Previous Names
  • wu:fd42f12
  • wu:fj22d06
  • zgc:101700
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have glutathione peroxidase activity. Predicted to be involved in several processes, including hydrogen peroxide catabolic process; response to hydrogen peroxide; and response to selenium ion. Predicted to localize to cytosol and mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cardiovascular system disease (multiple); hematologic cancer (multiple); nutritional deficiency disease (multiple); and pseudoxanthoma elasticum. Is expressed in digestive system; otic vesicle; and sensory system. Orthologous to human GPX1 (glutathione peroxidase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gpx1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hemolytic anemia due to glutathione peroxidase deficiency 614164
Associated With gpx1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000889 Glutathione peroxidase
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Glutathione peroxidase Thioredoxin-like superfamily
UniProtKB:Q66IE1 142
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations