Gene
cldn2
- ID
- ZDB-GENE-040912-26
- Name
- claudin 2
- Symbol
- cldn2 Nomenclature History
- Previous Names
-
- zgc:92260
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to localize to bicellular tight junction and plasma membrane. Is expressed in brain; eye; gonad; immune system; and liver. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 29. Orthologous to several human genes including CLDN2 (claudin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92260 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Azoospermia, obstructive, with nephrolithiasis | 301060 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin-2 | Claudin, conserved site | PMP-22/EMP/MP20/Claudin superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q66HX3
|
253 | ||||
|
UniProtKB:F1QKA9
|
270 |
Interactions and Pathways
No data available
Plasmids
No data available