Gene
taf6
- ID
- ZDB-GENE-040912-23
- Name
- TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
- Symbol
- taf6 Nomenclature History
- Previous Names
-
- wu:fb83e08
- wu:fj30b02
- zgc:92160
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable transcription coactivator activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF6 (TATA-box binding protein associated factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Phenotype Annotation (1994-2006)
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Alazami-Yuan syndrome | 617126 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004823 | TATA box binding protein associated factor (TAF), histone-like fold domain |
| Domain | IPR011442 | TAF6, C-terminal HEAT repeat domain |
| Family | IPR037796 | Transcription initiation factor TFIID subunit 6 |
| Homologous_superfamily | IPR009072 | Histone-fold |
| Homologous_superfamily | IPR046344 | TAF6, C-terminal HEAT repeat domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Histone-fold | TAF6, C-terminal HEAT repeat domain | TAF6, C-terminal HEAT repeat domain superfamily | TATA box binding protein associated factor (TAF), histone-like fold domain | Transcription initiation factor TFIID subunit 6 |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q66HZ5 | InterPro | 636 |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-30G3 | ZFIN Curated Data | |
| Contained in | BAC | CH211-273A5 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-184N3 | ZFIN Curated Data | |
| Encodes | EST | fb83e08 | ZFIN Curated Data | |
| Encodes | EST | fj30b02 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:92160 | ZFIN Curated Data |
1 - 6 of 6
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001004557 (1) | 2825 nt | ||
| Genomic | GenBank:BX927335 (1) | 164039 nt | ||
| Polypeptide | UniProtKB:Q66HZ5 (1) | 636 aa |
| Species | Symbol | Chromosome | Accession # | Evidence |
|---|---|---|---|---|
| Human | TAF6 | 7 | Amino acid sequence comparison (1) |
- Sharma, D., Sehgal, P., Mathew, S., Vellarikkal, S.K., Singh, A.R., Kapoor, S., Jayarajan, R., Scaria, V., Sivasubbu, S. (2019) A genome-wide map of circular RNAs in adult zebrafish. Scientific Reports. 9:3432
- Pijnappel, W.P., Kolkman, A., Baltissen, M.P., Heck, A.J., and Timmers, H.M. (2009) Quantitative mass spectrometry of TATA binding protein-containing complexes and subunit phosphorylations during the cell cycle. Proteome science. 7:46
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
- Amsterdam, A., Burgess, S., Golling, G., Chen, W., Sun, Z., Townsend, K., Farrington, S., Haldi, M., and Hopkins, N. (1999) A large-scale insertional mutagenesis screen in zebrafish. Genes & Development. 13(20):2713-2724
1 - 5 of 5
Show