Gene

gtf2h1

ID
ZDB-GENE-040912-164
Name
general transcription factor IIH, polypeptide 1
Symbol
gtf2h1 Nomenclature History
Previous Names
  • p62 (1)
  • zgc:92126
  • zmp:0000000569 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to contribute to DNA-dependent ATPase activity and RNA polymerase II CTD heptapeptide repeat kinase activity. Predicted to be involved in nucleic acid metabolic process and phosphorylation of RNA polymerase II C-terminal domain. Predicted to localize to transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gtf2h1 Human Ortholog
No data available
Associated With gtf2h1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005607 BSD domain
Domain IPR013876 TFIIH p62 subunit, N-terminal
Family IPR027079 TFIIH subunit Tfb1/GTF2H1
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035925 BSD domain superfamily
Domain Details Per Protein
Protein Length BSD domain BSD domain superfamily PH-like domain superfamily TFIIH p62 subunit, N-terminal TFIIH subunit Tfb1/GTF2H1
UniProtKB:Q66I03 550
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA gtf2h1-201 (1) Ensembl 2,461 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations