Gene

dnai1.1

ID
ZDB-GENE-040910-7
Name
dynein, axonemal, intermediate chain 1, paralog 1
Symbol
dnai1.1 Nomenclature History
Previous Names
  • dnai1
  • si:ch73-182i17.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have dynein heavy chain binding activity and dynein light chain binding activity. Involved in determination of heart left/right asymmetry. Predicted to localize to outer dynein arm. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhao et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnai1.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 1 Alliance Ciliary dyskinesia, primary, 1, with or without situs inversus 244400
Associated With dnai1.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length WD40 repeat WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E9QCC1 169
UniProtKB:A0A0M3HEN6 553
UniProtKB:E9QFM9 583
UniProtKB:E9QGT5 225
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations