Gene

srp68

ID

ZDB-GENE-040831-3

Name

signal recognition particle 68

Symbol

srp68 Nomenclature History

Previous Names

zgc:92573

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable signal recognition particle binding activity. Predicted to act upstream of or within SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Orthologous to human SRP68 (signal recognition particle 68).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7160947 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With srp68 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Neutropenia, severe congenital, 10, autosomal recessive	620534

Associated With srp68 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR034652	Signal recognition particle subunit SRP68, RNA-binding domain
Family	IPR026258	Signal recognition particle subunit SRP68
Homologous_superfamily	IPR038253	SRP68, N-terminal domain superfamily