Gene
snrnp70
- ID
- ZDB-GENE-040825-2
- Name
- small nuclear ribonucleoprotein 70 (U1)
- Symbol
- snrnp70 Nomenclature History
- Previous Names
-
- snrp70
- U1 small ribonucleoprotein 70kd (1)
- wu:fc20b04
- zgc:136450
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable U1 snRNA binding activity and mRNA binding activity. Acts upstream of or within hematopoietic stem cell differentiation. Predicted to be located in nucleus. Predicted to be part of U1 snRNP and U2-type prespliceosome. Is expressed in central nervous system; hematopoietic stem cell; and motor neurons. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147833 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR022023 | U1 small nuclear ribonucleoprotein of 70kDa N-terminal |
| Domain | IPR034143 | snRNP70, RNA recognition motif |
| Family | IPR051183 | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | snRNP70, RNA recognition motif | U1 small nuclear ribonucleoprotein of 70kDa N-terminal | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DRE8 | InterPro | 495 | ||||||
| UniProtKB:E7EY23 | InterPro | 162 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
snrnp70-201
(1)
|
Ensembl | 2,488 nt | ||
| mRNA |
snrnp70-202
(1)
|
Ensembl | 885 nt |
Interactions and Pathways
No data available
Plasmids
No data available