Gene
her12
- ID
- ZDB-GENE-040824-5
- Name
- hairy-related 12
- Symbol
- her12 Nomenclature History
- Previous Names
-
- Hes5c (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in Notch signaling pathway; brain development; and somitogenesis. Predicted to localize to nucleus. Is expressed in several structures, including mesoderm; nervous system; neural plate; tail bud; and trunk vasculature. Orthologous to human HES5 (hes family bHLH transcription factor 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904047 (35 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Orange domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6TA36
|
155 |
Interactions and Pathways
No data available
Plasmids
No data available