Gene
lhb
- ID
- ZDB-GENE-040806-2
- Name
- luteinizing hormone subunit beta
- Symbol
- lhb Nomenclature History
- Previous Names
-
- LHB
- Gth II
- gthII
- LH Beta
- zgc:92312
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Exhibits hormone activity. Involved in female gonad development; gamete generation; and sex determination. Predicted to localize to cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 23 with or without anosmia. Is expressed in several structures, including endocrine system; female organism; kidney; liver; and male organism. Orthologous to several human genes including LHB (luteinizing hormone subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 53 figures from 36 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 23 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 23 with or without anosmia | 228300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | Glycoprotein hormone subunit beta | Gonadotropin, beta subunit | Gonadotropin, beta subunit, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q6TCF5
|
140 |
Interactions and Pathways
No data available
Plasmids
No data available