Gene
fshb
- ID
- ZDB-GENE-040806-1
- Name
- follicle stimulating hormone subunit beta
- Symbol
- fshb Nomenclature History
- Previous Names
-
- FSHB
- FSH Beta
- Gth I
- gthI
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits hormone activity. Involved in ovarian follicle development; sex determination; and spermatogenesis. Predicted to localize to cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in amenorrhea and hypogonadotropic hypogonadism 24 without anosmia. Is expressed in several structures, including brain; endocrine system; female organism; kidney; and male organism. Orthologous to human FSHB (follicle stimulating hormone subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 47 figures from 32 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hypogonadotropic hypogonadism 24 without anosmia | Alliance | Hypogonadotropic hypogonadism 24 without anosmia | 229070 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Cystine-knot cytokine | Glycoprotein hormone subunit beta | Gonadotropin, beta subunit | Gonadotropin, beta subunit, conserved site |
---|---|---|---|---|---|
UniProtKB:Q6TCF7
|
130 |
Interactions and Pathways
No data available
Plasmids
No data available