Gene
fshb
- ID
- ZDB-GENE-040806-1
- Name
- follicle stimulating hormone subunit beta
- Symbol
- fshb Nomenclature History
- Previous Names
-
- FSHB
- FSH Beta
- Gth I
- gthI
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Enables hormone activity. Acts upstream of or within ovarian follicle development; sex determination; and spermatogenesis. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including brain; endocrine system; female organism; kidney; and male organism. Human ortholog(s) of this gene implicated in amenorrhea and hypogonadotropic hypogonadism 24 without anosmia. Orthologous to human FSHB (follicle stimulating hormone subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 48 figures from 33 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 24 without anosmia | Alliance | Hypogonadotropic hypogonadism 24 without anosmia | 229070 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine-knot cytokine | Glycoprotein hormone subunit beta | Gonadotropin, beta subunit | Gonadotropin, beta subunit, conserved site |
|---|---|---|---|---|---|---|
| UniProtKB:Q6TCF7 | InterPro | 130 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available