Gene
brf2
- ID
- ZDB-GENE-040801-43
- Name
- BRF2 general transcription factor IIIB subunit
- Symbol
- brf2 Nomenclature History
- Previous Names
-
- si:ch211-271b8.2
- wu:fj22c04
- zgc:100856
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II general transcription initiation factor activity; RNA polymerase III type 3 promoter sequence-specific DNA binding activity; and TBP-class protein binding activity. Predicted to be involved in cellular response to oxidative stress and regulation of transcription by RNA polymerase III. Predicted to act upstream of or within transcription preinitiation complex assembly. Predicted to be part of transcription factor TFIIIB complex and transcription preinitiation complex. Predicted to be active in nucleus. Orthologous to human BRF2 (BRF2 general transcription factor IIIB subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903375 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | BRF2-like, C-terminal | Cyclin-like superfamily | Transcription factor TFIIB | Zinc finger, TFIIB-type |
|---|---|---|---|---|---|---|
| UniProtKB:F1QIW1 | InterPro | 423 | ||||
| UniProtKB:A8KBY2 | InterPro | 423 |
Interactions and Pathways
No data available
Plasmids
No data available