Gene
slc38a7
- ID
- ZDB-GENE-040801-266
- Name
- solute carrier family 38 member 7
- Symbol
- slc38a7 Nomenclature History
- Previous Names
-
- cb389 (1)
- fb71c10
- fi23b07
- sb:cb389
- wu:fb71c10
- wu:fi23b07
- zgc:100802
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable L-asparagine:sodium symporter activity and L-glutamine:sodium symporter activity. Predicted to be involved in amino acid transmembrane transport; asparagine transport; and glutamine transport. Predicted to act upstream of or within amino acid transport and sodium ion transport. Predicted to be located in lysosomal membrane. Predicted to be active in membrane. Is expressed in mesoderm; musculature system; myotome; somite; and yolk syncytial layer. Orthologous to human SLC38A7 (solute carrier family 38 member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb389 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| a335 | Allele with multiple variants | Unknown | Unknown | CRISPR |
1 - 1 of 1
Show
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-slc38a7 | Thyme et al., 2019 | |
| CRISPR2-slc38a7 | Thyme et al., 2019 | |
| CRISPR3-slc38a7 | Thyme et al., 2019 | |
| CRISPR4-slc38a7 | Thyme et al., 2019 |
1 - 4 of 4
Show
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013057 | Amino acid transporter, transmembrane domain |
1 - 1 of 1
Domain Details Per Protein
| Protein | Additional Resources | Length | Amino acid transporter, transmembrane domain |
|---|---|---|---|
| UniProtKB:Q6DEL1 | InterPro | 465 | |
| UniProtKB:F1QUV9 | InterPro | 465 |
1 - 2 of 2
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc38a7-201
(1)
|
Ensembl | 4,488 nt | ||
| mRNA |
slc38a7-202
(1)
|
Ensembl | 2,898 nt | ||
| mRNA |
slc38a7-203
(1)
|
Ensembl | 2,851 nt |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-122F10 | ZFIN Curated Data | |
| Encodes | EST | cb389 | Thisse et al., 2001 | |
| Encodes | EST | fb71c10 | ||
| Encodes | EST | fi23b07 | ||
| Encodes | cDNA | MGC:100802 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:113883 | ZFIN Curated Data |
1 - 6 of 6
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001003648 (1) | 2690 nt | ||
| Genomic | GenBank:BX957362 (2) | 191638 nt | ||
| Polypeptide | UniProtKB:F1QUV9 (1) | 465 aa |
- Thyme, S.B., Pieper, L.M., Li, E.H., Pandey, S., Wang, Y., Morris, N.S., Sha, C., Choi, J.W., Herrera, K.J., Soucy, E.R., Zimmerman, S., Randlett, O., Greenwood, J., McCarroll, S.A., Schier, A.F. (2019) Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Cell. 177(2):478-491.e20
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 4 of 4
Show