Gene

kptn

ID
ZDB-GENE-040801-258
Name
kaptin (actin binding protein)
Symbol
kptn Nomenclature History
Previous Names
  • wu:fc13b08
  • wu:fc13b09
  • zgc:100793
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in cellular response to amino acid starvation and negative regulation of TORC1 signaling. Predicted to colocalize with filamentous actin. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human KPTN (kaptin, actin binding protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kptn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 41 Alliance Intellectual developmental disorder, autosomal recessive 41 615637
Associated With kptn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR029982 Kaptin
Homologous_superfamily IPR028994 Integrin alpha, N-terminal
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations