Gene
ikzf5
- ID
- ZDB-GENE-040801-209
- Name
- IKAROS family zinc finger 5
- Symbol
- ikzf5 Nomenclature History
- Previous Names
-
- wu:fb55f09
- zgc:92405 (1)
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Acts upstream of or within determination of intestine left/right asymmetry; determination of left/right asymmetry in lateral mesoderm; and determination of pancreatic left/right asymmetry. Predicted to be located in nucleus. Is expressed in several structures, including brain; digestive system; eye; pharyngeal arch cartilage; and thymus. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human IKZF5 (IKAROS family zinc finger 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from John et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Thrombocytopenia, autosomal dominant, 7 | 619130 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|
|
UniProtKB:C4XVB6
|
419 | ||
|
UniProtKB:Q6DBW0
|
419 |
Interactions and Pathways
No data available
Plasmids
No data available