Gene
nadk2
- ID
- ZDB-GENE-040801-202
- Name
- NAD kinase 2, mitochondrial
- Symbol
- nadk2 Nomenclature History
- Previous Names
-
- nadkd1
- zgc:92417
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; NAD+ kinase activity; and protein homodimerization activity. Predicted to be involved in NAD metabolic process; NADP biosynthetic process; and phosphorylation. Predicted to localize to mitochondrion. Orthologous to human NADK2 (NAD kinase 2, mitochondrial).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92417 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 2,4-dienoyl-CoA reductase deficiency | 616034 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002504 | NAD kinase |
| Family | IPR012355 | NAD kinase 2, mitochondrial |
| Homologous_superfamily | IPR016064 | NAD kinase/diacylglycerol kinase-like domain superfamily |
| Homologous_superfamily | IPR017437 | ATP-NAD kinase, PpnK-type, C-terminal |
| Homologous_superfamily | IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal |
Domain Details Per Protein
| Protein | Length | ATP-NAD kinase, PpnK-type, C-terminal | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | NAD kinase | NAD kinase 2, mitochondrial | NAD kinase/diacylglycerol kinase-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B8E7
|
441 | |||||
|
UniProtKB:A0A8M2B840
|
446 | |||||
|
UniProtKB:A0A8M3ATU3
|
294 | |||||
|
UniProtKB:A0A0R4IKV3
|
430 |
Interactions and Pathways
No data available
Plasmids
No data available