Gene
dusp2
- ID
- ZDB-GENE-040801-188
- Name
- dual specificity phosphatase 2
- Symbol
- dusp2 Nomenclature History
- Previous Names
-
- wu:fj40g04
- zgc:91929
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable phosphoprotein phosphatase activity. Acts upstream of or within axon regeneration and negative regulation of JNK cascade. Predicted to be active in cytoplasm and nucleus. Is expressed in hindbrain neural plate; mucus secreting cell; nervous system; and presumptive rhombomere 4. Orthologous to human DUSP2 (dual specificity phosphatase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91929 (13 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000340 | Dual specificity phosphatase, catalytic domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR001763 | Rhodanese-like domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR020422 | Dual specificity protein phosphatase domain |
| Family | IPR008343 | Mitogen-activated protein (MAP) kinase phosphatase |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR036873 | Rhodanese-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Dual specificity phosphatase, catalytic domain | Dual specificity protein phosphatase domain | Mitogen-activated protein (MAP) kinase phosphatase | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Rhodanese-like domain | Rhodanese-like domain superfamily | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DBR5
|
333 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available