Gene
rab18b
- ID
- ZDB-GENE-040801-185
- Name
- RAB18B, member RAS oncogene family
- Symbol
- rab18b Nomenclature History
- Previous Names
-
- zgc:92523
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activity. Involved in brain development and eye development. Acts upstream of or within chordate embryonic development. Predicted to be located in cis-Golgi network membrane; endoplasmic reticulum membrane; and lipid droplet. Predicted to be active in Golgi apparatus. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bem et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bem et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Warburg micro syndrome 3 | Alliance | Warburg micro syndrome 3 | 614222 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rab | Sigma-54 interaction domain, ATP-binding site 1 | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DHC1 | InterPro | 205 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rab18b-201
(1)
|
Ensembl | 1,805 nt |
Interactions and Pathways
No data available
Plasmids