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General Information
ZIRC
ZFIN ID: ZDB-GENE-040801-185
Gene Name: RAB18B, member RAS oncogene family
Gene Symbol: rab18b    Nomenclature History

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Previous Name: zgc:92523

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have GTPase activity. Involved in brain development; chordate embryonic development; and eye development. Predicted to localize to the Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
Genome Resources: Alliance (1),  Gene:445055 (1),  Ensembl(GRCz11):ENSDARG00000098344 (1)
GENE EXPRESSION
All Expression Data: Fig. S7 from Bem et al., 2011
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-rab18b N/A 1
MO2-rab18b N/A 1
DISEASE ASSOCIATED WITH rab18b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Warburg micro syndrome 3 Alliance Warburg micro syndrome 3 614222
DISEASE ASSOCIATED WITH rab18b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process brain development (more)
Cellular Component endomembrane system (more)
Molecular Function GTPase activity (more)
GO Terms (all 13)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rab18b-201 (1)    Ensembl 1805
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM rab18b No data available
MARKER RELATIONSHIPS
rab18b Contained in: [Fosmid] ZFOS-844F9 (1)
rab18b Encodes: [cDNA] MGC:92523 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003449 (1) 1735 bp
Genomic GenBank:CU694527 (1) 38763 bp
Select Tool
Polypeptide UniProtKB:Q6DHC1 (1) 205 aa
Sequence Clusters UniGene:79683 (1)
Sequence Information (all 10)
ORTHOLOGY for rab18b ( Chr: 2 )
CITATIONS (19)