Gene

rab18b

ID
ZDB-GENE-040801-185
Name
RAB18B, member RAS oncogene family
Symbol
rab18b Nomenclature History
Previous Names
  • zgc:92523
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have GTPase activity. Involved in brain development; chordate embryonic development; and eye development. Predicted to localize to Golgi apparatus and lipid droplet. Is expressed in brain; heart tube; optic cup; retina; and retinal inner nuclear layer. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Orthologous to human RAB18 (RAB18, member RAS oncogene family).
Genome Resources
Note
None
Expression
All Expression Data
from Bem et al., 2011
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Bem et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rab18b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Warburg micro syndrome 3 Alliance Warburg micro syndrome 3 614222
Associated With rab18b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR025662 Sigma-54 interaction domain, ATP-binding site 1
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Sigma-54 interaction domain, ATP-binding site 1 Small GTPase Small GTP-binding protein domain
UniProtKB:Q6DHC1 205
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations