Gene
timm8a
- ID
- ZDB-GENE-040801-158
- Name
- translocase of inner mitochondrial membrane 8 homolog A (yeast)
- Symbol
- timm8a Nomenclature History
- Previous Names
-
- im:6896085
- zgc:100916
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to act upstream of or within protein transport. Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Orthologous to human TIMM8A (translocase of inner mitochondrial membrane 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6896085 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| deafness-dystonia-optic neuronopathy syndrome | Alliance | Mohr-Tranebjaerg syndrome | 304700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tim10-like | Tim10-like domain superfamily |
|---|---|---|---|
|
UniProtKB:Q6DEM5
|
90 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timm8a-201
(1)
|
Ensembl | 1,057 nt |
Interactions and Pathways
No data available
Plasmids
No data available