Gene
timm8a
- ID
- ZDB-GENE-040801-158
- Name
- translocase of inner mitochondrial membrane 8 homolog A (yeast)
- Symbol
- timm8a Nomenclature History
- Previous Names
-
- im:6896085
- zgc:100916
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Predicted to be involved in chaperone-mediated protein transport. Predicted to localize to mitochondrial inner membrane and mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in deafness-dystonia-optic neuronopathy syndrome and dystonia. Orthologous to human TIMM8A (translocase of inner mitochondrial membrane 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6896085 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| deafness-dystonia-optic neuronopathy syndrome | Alliance | Mohr-Tranebjaerg syndrome | 304700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tim10-like | Tim10-like domain superfamily |
|---|---|---|---|
|
UniProtKB:Q6DEM5
|
90 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
timm8a-201
(1)
|
Ensembl | 1,057 nt |
Interactions and Pathways
No data available
Plasmids
No data available