Gene

hnmt

ID
ZDB-GENE-040801-157
Name
histamine N-methyltransferase
Symbol
hnmt Nomenclature History
Previous Names
  • zgc:100917
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have histamine N-methyltransferase activity. Predicted to be involved in histamine catabolic process and methylation. Predicted to localize to cytoplasm. Is expressed in adaxial cell and muscle pioneer. Human ortholog(s) of this gene implicated in Parkinson's disease; asthma; atopic dermatitis; autosomal recessive non-syndromic intellectual disability; and essential tremor. Orthologous to human HNMT (histamine N-methyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hnmt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
asthma Alliance {Asthma, susceptibility to} 600807
Mental retardation, autosomal recessive 51 616739
Associated With hnmt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR016673 Histamine N-methyltransferase-like
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Domain Details Per Protein
Protein Length Histamine N-methyltransferase-like S-adenosyl-L-methionine-dependent methyltransferase
UniProtKB:B0V2U7 331
UniProtKB:F1Q6M8 292
UniProtKB:Q6DC37 292
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations