Gene
nek7
- ID
- ZDB-GENE-040801-136
- Name
- NIMA-related kinase 7
- Symbol
- nek7 Nomenclature History
- Previous Names
-
- wu:fj68f02
- zgc:100962
- zgc:92175
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in positive regulation of NLRP3 inflammasome complex assembly and positive regulation of telomere maintenance via telomerase. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in centrosome and spindle pole. Predicted to be active in nucleus. Orthologous to human NEK7 (NIMA related kinase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Serine-threonine/tyrosine-protein kinase, catalytic domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DEH7 | InterPro | 297 |
Interactions and Pathways
No data available
Plasmids
No data available