Gene

dpm1

ID
ZDB-GENE-040801-115
Name
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
Symbol
dpm1 Nomenclature History
Previous Names
  • zgc:101018
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable dolichyl-phosphate beta-D-mannosyltransferase activity and dolichyl-phosphate-mannose-protein mannosyltransferase activity. Acts upstream of or within muscle structure development. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in brain; cloaca; pronephric duct; solid lens vesicle; and vertical myoseptum. Used to study congenital disorder of glycosylation type I. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Orthologous to human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa24304Allele with one point mutationUnknownPremature StopENU
sa30737Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
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Human Disease
Associated With dpm1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation Ie Alliance Congenital disorder of glycosylation, type Ie 608799
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Associated With dpm1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001173 Glycosyltransferase 2-like
Family IPR039528 DPM1-like
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
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Domain Details Per Protein
Protein Length DPM1-like Glycosyltransferase 2-like Nucleotide-diphospho-sugar transferases
UniProtKB:Q6DEJ9 250
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 23
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dpm1-201 (1) Ensembl 1,297 nt
ncRNA dpm1-002 (1) Ensembl 797 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-104F13ZFIN Curated Data
EncodesESTIMAGE:7137664Thisse et al., 2004
EncodescDNAMGC:101018ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanDPM120
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
MouseDpm22
Amino acid sequence comparison (1)
Citations
1 - 7 of 7
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