ZFIN is now using GRCz12tu for Genomic Data
Gene
b4galt7
- ID
- ZDB-GENE-040727-3
- Name
- xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- Symbol
- b4galt7 Nomenclature History
- Previous Names
-
- zgc:110571
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable xylosylprotein 4-beta-galactosyltransferase activity. Acts upstream of or within several processes, including hatching behavior; proteoglycan biosynthetic process; and thigmotaxis. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Predicted to be active in Golgi apparatus. Used to study Ehlers-Danlos syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and Ehlers-Danlos syndrome spondylodysplastic type 1. Orthologous to human B4GALT7 (beta-1,4-galactosyltransferase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Delbaere et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ehlers-Danlos syndrome spondylodysplastic type 1 | Alliance | Ehlers-Danlos syndrome, spondylodysplastic type, 1 | 130070 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Ehlers-Danlos syndrome | b4galt7hi1516Tg/hi1516Tg | standard conditions | Nissen et al., 2006 |
| Ehlers-Danlos syndrome | b4galt7hi4063aTg/hi4063aTg | standard conditions | Nissen et al., 2006 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Beta-1,4-galactosyltransferase | Galactosyltransferase, C-terminal | Galactosyltransferase, N-terminal | Nucleotide-diphospho-sugar transferases |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PZ57 | InterPro | 328 | ||||
| UniProtKB:Q6DRL9 | InterPro | 317 | ||||
| UniProtKB:A0AB32T339 | InterPro | 326 | ||||
| UniProtKB:A0AB32T616 | InterPro | 315 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
b4galt7-201
(1)
|
Ensembl | 1,607 nt | ||
| mRNA |
b4galt7-202
(1)
|
Ensembl | 4,425 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers