ZFIN is now using GRCz12tu for Genomic Data
Gene
nr6a1b
- ID
- ZDB-GENE-040724-202
- Name
- nuclear receptor subfamily 6, group A, member 1b
- Symbol
- nr6a1b Nomenclature History
- Previous Names
-
- GCNF-B (1)
- si:ch211-167p9.1
- zgc:114189
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable estrogen response element binding activity; nuclear receptor activity; and protein homodimerization activity. Predicted to be involved in cell migration; nervous system development; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including basal plate midbrain region; nervous system; pronephric duct; ventral mesenchyme; and ventral mesoderm. Orthologous to human NR6A1 (nuclear receptor subfamily 6 group A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017610 (24 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR050200 | Nuclear hormone receptor family NR3 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR3 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q4V8R7 | InterPro | 455 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nr6a1b-201
(1)
|
Ensembl | 1,501 nt | ||
| mRNA |
nr6a1b-202
(1)
|
Ensembl | 1,317 nt |
Interactions and Pathways
No data available
Plasmids
No data available