Gene
ift74
- ID
- ZDB-GENE-040718-81
- Name
- intraflagellar transport 74
- Symbol
- ift74 Nomenclature History
- Previous Names
-
- zgc:92052
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have beta-tubulin binding activity. Involved in gastrulation and pronephric proximal tubule development. Predicted to localize to intraciliary transport particle B. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome. Orthologous to human IFT74 (intraflagellar transport 74).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhu et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bardet-Biedl syndrome 22 | Alliance | Bardet-Biedl syndrome 22 | 617119 |
| spermatogenic failure 58 | Alliance | Spermatogenic failure 58 | 619585 |
| Joubert syndrome 40 | 619582 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR029602 | Intraflagellar transport protein 74 |
Domain Details Per Protein
| Protein | Length | Intraflagellar transport protein 74 |
|---|---|---|
|
UniProtKB:A0A8M9PXA7
|
583 | |
|
UniProtKB:Q6DHU7
|
486 | |
|
UniProtKB:A0A8M9Q8D0
|
603 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available