ZFIN is now using GRCz12tu for Genomic Data
Gene
nelfe
- ID
- ZDB-GENE-040718-69
- Name
- negative elongation factor complex member E
- Symbol
- nelfe Nomenclature History
- Previous Names
-
- rdbp
- zgc:92496
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable RNA binding activity and translation elongation factor activity. Acts upstream of or within positive regulation of hematopoietic stem cell differentiation and regulation of granulocyte differentiation. Predicted to be located in chromosome and nucleus. Predicted to be part of NELF complex. Orthologous to human NELFE (negative elongation factor complex member E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92496 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR034637 | Negative elongation factor E, RNA recognition motif |
| Family | IPR033102 | Negative elongation factor E |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Negative elongation factor E | Negative elongation factor E, RNA recognition motif | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PN91 | InterPro | 378 | |||||
| UniProtKB:Q1LWQ2 | InterPro | 346 | |||||
| UniProtKB:Q6DHD7 | InterPro | 346 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
nelfe-202
(1)
|
Ensembl | 322 nt | ||
| mRNA |
nelfe-201
(1)
|
Ensembl | 1,202 nt | ||
| mRNA |
nelfe-203
(1)
|
Ensembl | 1,638 nt | ||
| mRNA |
nelfe-204
(1)
|
Ensembl | 779 nt | ||
| mRNA |
nelfe-205
(1)
|
Ensembl | 3,119 nt | ||
| mRNA |
nelfe-206
(1)
|
Ensembl | 2,928 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers