Gene
ica1
- ID
- ZDB-GENE-040718-490
- Name
- islet cell autoantigen 1
- Symbol
- ica1 Nomenclature History
- Previous Names
-
- zgc:92566 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to be located in cytoplasm; endomembrane system; and intracellular membrane-bounded organelle. Predicted to be active in Golgi apparatus. Is expressed in central nervous system; neurons; rhombomere; and ventricular zone. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ICA1 (islet cell autoantigen 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92566 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | Arfaptin homology (AH) domain | Islet cell autoantigen 1/Ica1-like | Islet cell autoantigen Ica1, C-terminal |
|---|---|---|---|---|---|
|
UniProtKB:E7EXU4
|
|||||
|
UniProtKB:Q6DHA0
|
449 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance