Gene
dnase1
- ID
- ZDB-GENE-040718-423
- Name
- deoxyribonuclease I
- Symbol
- dnase1 Nomenclature History
- Previous Names
-
- zgc:92440 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in DNA catabolic process, endonucleolytic. Predicted to act upstream of or within DNA catabolic process. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to several human genes including DNASE1 (deoxyribonuclease 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92440 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| systemic lupus erythematosus | Alliance | {Systemic lupus erythematosus, susceptibility to} | 152700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Deoxyribonuclease I | Deoxyribonuclease I, active site | Endonuclease/exonuclease/phosphatase | Endonuclease/exonuclease/phosphatase superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6DG72
|
278 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnase1-201
(1)
|
Ensembl | 1,309 nt |
Interactions and Pathways
No data available
Plasmids
No data available