Gene

slc1a1

ID
ZDB-GENE-040718-414
Name
solute carrier family 1 member 1
Symbol
slc1a1 Nomenclature History
Previous Names
  • EAAT3 (1)
  • zgc:91959
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have symporter activity. Predicted to localize to integral component of membrane. Is expressed in cerebellum; optic tectum; and telencephalon. Human ortholog(s) of this gene implicated in dicarboxylic aminoaciduria and schizophrenia 18. Orthologous to human SLC1A1 (solute carrier family 1 member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc1a1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dicarboxylic aminoaciduria Alliance Dicarboxylic aminoaciduria 222730
schizophrenia 18 Alliance {?Schizophrenia susceptibility 18} 615232
Associated With slc1a1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018107 Sodium:dicarboxylate symporter, conserved site
Family IPR001991 Sodium:dicarboxylate symporter
Family IPR050746 Dicarboxylate/Amino Acid:Cation Symporter
Homologous_superfamily IPR036458 Sodium:dicarboxylate symporter superfamily
Domain Details Per Protein
Protein Length Dicarboxylate/Amino Acid:Cation Symporter Sodium:dicarboxylate symporter Sodium:dicarboxylate symporter, conserved site Sodium:dicarboxylate symporter superfamily
UniProtKB:D7RVR6 528
UniProtKB:A0A8M9QGS6 329
UniProtKB:Q6DG02 526
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
aberrant processed transcript slc1a1-202 (1) Havana 779 nt
mRNA slc1a1-201 (1) Havana 2966 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations