Gene
acss2
- ID
- ZDB-GENE-040718-388
- Name
- acyl-CoA synthetase short chain family member 2
- Symbol
- acss2 Nomenclature History
- Previous Names
-
- fa04c03
- fj80b06
- fj80h04
- wu:fa04c03
- wu:fj80b06
- wu:fj80h04
- zgc:92200
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have AMP binding activity; ATP binding activity; and acetate-CoA ligase activity. Predicted to be involved in acetyl-CoA biosynthetic process from acetate. Human ortholog(s) of this gene implicated in orofacial cleft. Orthologous to human ACSS2 (acyl-CoA synthetase short chain family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Tilghman et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020845 | AMP-binding, conserved site |
| Domain | IPR000873 | AMP-dependent synthetase/ligase domain |
| Domain | IPR025110 | AMP-binding enzyme, C-terminal domain |
| Domain | IPR032387 | Acetyl-coenzyme A synthetase, N-terminal domain |
| Family | IPR011904 | Acetate-CoA ligase |
| Homologous_superfamily | IPR042099 | ANL, N-terminal domain |
| Homologous_superfamily | IPR045851 | AMP-binding enzyme, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Acetate-CoA ligase | Acetyl-coenzyme A synthetase, N-terminal domain | AMP-binding, conserved site | AMP-binding enzyme, C-terminal domain | AMP-binding enzyme, C-terminal domain superfamily | AMP-dependent synthetase/ligase domain | ANL, N-terminal domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A2R8Q6G5
|
682 | |||||||
|
UniProtKB:F1QAA7
|
698 |
Interactions and Pathways
No data available
Plasmids
No data available