Gene
tnfsf10
- ID
- ZDB-GENE-040718-335
- Name
- TNF superfamily member 10
- Symbol
- tnfsf10 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have cytokine activity; metal ion binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of extrinsic apoptotic signaling pathway. Predicted to localize to extracellular space and membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Is expressed in anterior lateral line neuromast; brain; and posterior lateral line neuromast. Orthologous to human TNFSF10 (TNF superfamily member 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Eimon et al., 2006
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Serbanovic-Canic et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tumour necrosis factor, conserved site | Tumour necrosis factor domain | Tumour necrosis factor ligand 10/11 | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6DHG9
|
299 | ||||
|
UniProtKB:A0A2R8QAD8
|
286 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfsf10-201
(1)
|
Ensembl | 1,879 nt | ||
| mRNA |
tnfsf10-202
(1)
|
Ensembl | 1,836 nt |
Interactions and Pathways
No data available
Plasmids
No data available