Gene

cryba2b

ID
ZDB-GENE-040718-324
Name
crystallin, beta A2b
Symbol
cryba2b Nomenclature History
Previous Names
  • im:7144156 (1)
  • zgc:92722
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in lens and solid lens vesicle. Human ortholog(s) of this gene implicated in cataract 42. Orthologous to human CRYBA2 (crystallin beta A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa17130Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With cryba2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 42 Alliance ?Cataract 42 115900
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Associated With cryba2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001064 Beta/gamma crystallin
Family IPR050252 Beta/Gamma-Crystallin
Homologous_superfamily IPR011024 Gamma-crystallin-like
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Domain Details Per Protein
Protein Additional Resources Length Beta/gamma crystallin Beta/Gamma-Crystallin Gamma-crystallin-like
UniProtKB:Q45FX9 InterPro 197
UniProtKB:Q6DGY2 InterPro 197
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 9
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cryba2b-201 (1) Ensembl 803 nt
mRNA cryba2b-202 (1) Ensembl 840 nt
mRNA cryba2b-205 (1) Ensembl 991 nt
ncRNA cryba2b-003 (1) Ensembl 854 nt
ncRNA cryba2b-004 (1) Ensembl 715 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-69O16ZFIN Curated Data
EncodesESTIMAGE:7144156Thisse et al., 2004
EncodescDNAMGC:92722ZFIN Curated Data
1 - 3 of 3
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanCRYBA22
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseCryba21
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 22
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